The BIO5 Institute

Medicinal & Natural Products Chemistry

Degrees Awarded: MS / Ph.D. (Pharmaceutical Sciences)

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Hurley, Laurence: Discovery and Development of Novel Anticancer Drugs
Jacobson, Elaine: We are developing target specific drugs for skin cancer prevention. Presently we are targeting a unique feature of UV light induced damage in skin dermal proteins in the extracellular matrix, such as collagen, that absorb light and generate ROS. We are also developing agents that scavenge reactive carbonyl species formed in skin by UV light. These studies span both basic and translational aspects of skin cancer prevention.
Jacobson, Myron: I am involved in the development of drugs for the treatment and prevention of skin damage, for a number of skin conditions that involve a weakened skin barrier and for the reduction of the risk of heart attack and stroke. I serve as the associate editor of the Journal of Pharmacology & Experimental Therapeutics and as a member of the editorial board for the journal Pharmaceutical Research.
Maggiora, Gerald: Interests cover a wide range of areas in biochemistry and medicinal chemistry including cheminformatics, exploratory data analysis and data mining, pattern recognition, computer-aided drug design, protein structure and function, and biochemical systems theory.
Wondrak, Georg: Research includes skin photocarcinogenesis and its dependence on accumulative chemical damage from cellular photooxidative and carbonyl stress. Research intends to develop novel agents for skin photoprotection and anti-melanoma intervention.
Yang, Danzhou: Target interactions of anti-cancer drugs and rational drug design

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