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Medicinal Chemistry

Faculty:

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Flynn, Gary: Structure-based design methods for the discovery of potential drug candidates
Ghosh, Indraneel: The broad objective of our work is to use a repertoire of de novo protein design, directed evolution, and small-molecule approaches to target human disease.
Gokhale, Vijay:
Hulme, Christopher: Organic and Medicinal Chemistry
Jacobson, Elaine: We are developing target specific drugs for skin cancer prevention. Presently we are targeting a unique feature of UV light induced damage in skin dermal proteins in the extracellular matrix, such as collagen, that absorb light and generate ROS. We are also developing agents that scavenge reactive carbonyl species formed in skin by UV light. These studies span both basic and translational aspects of skin cancer prevention.
Jacobson, Myron: I am involved in the development of drugs for the treatment and prevention of skin damage, for a number of skin conditions that involve a weakened skin barrier and for the reduction of the risk of heart attack and stroke. I serve as the associate editor of the Journal of Pharmacology & Experimental Therapeutics and as a member of the editorial board for the journal Pharmaceutical Research.

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