The BIO5 Institute

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Metabolism and Metabolic Control

Faculty:

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Baumgard, Lance: Nutritional Physiology Research focus will be on improving efficiency of animal production and to better understand how nutrient utilization is regulated. Of special interest is how homeostatic and homeorhetic systems control nutrient partitioning to support different physiological states. Areas of research will involve nutritional, biochemical, molecular, and endocrine aspects of metabolism. Lactation: Research will concentrate on mechanisms regulating milk synthesis and production of milk components. This will involve studying the process of how milk fat is synthesized and how environmental factors, including nutrition and ambient temperature, regulate both the yield and composition of milk fat. Goals are to discover techniques to manipulate milk fat production to improve animal performance and well-being and improve the healthfulness of dairy products. Continued efforts will be made to identify the biological mechanisms by which selection mediates increased milk yield and to understand the variation and improve the efficiency of milk production. Growth: Research will focus on understanding lipid metabolism during growth. This will involve studying the process of how nutrients are coordinated and partitioned between accretion of lean and adipose tissue. Efforts will be made to manipulate lipid metabolism to improve efficiency and healthfulness of animal products
Brooks, Heddwen: Research focuses on the molecular regulation of the kidney, with a focus on diseases such as diabetes.
Cherrington, Nathan: Transporter Regulation and Molecular Toxicology
Cusanovich, Michael: The Cusanovich laboratory focus on studies of protein structure and function, with an emphasis on biological recognition (protein-protein interactions), the role and mechanisms of protein dynamics in biologically relevant processes, and aspects of bacterial metabolism.
Dornhaus, Anna: Organization in groups, how collective behaviors emerge from the actions and interactions of individuals, is the main interest of Anna Dornhaus. As model systems she studies social insect colonies (bumble bees, honey bees and ants) in the laboratory and in the field, as well as using mathematical and individual-based modeling approaches. She investigates mechanisms of coordination in foraging, collective decision-making, task allocation and division of labor. Her recent work has included the role of communication in the allocation of foragers to food sources; the evolution of different recruitment systems in different species of bees, and how ecology shapes these recruitment systems; house hunting strategies in ants; speed-accuracy trade offs in decision-making; and whether different group sizes necessitate different organizational strategies. Please check my homepage for details on individual projects.
Gillies, Robert: The Tumor Microenvironment, Anti-Cancer Therapies, and Molecular Imaging
Griffin, Kurt: Prevention and early treatment of Diabetes. The role of protein kinase A (PKA) signaling in tumorigenesis
Henriksen, Erik: Our research group is interested in the regulation of carbohydrate and protein metabolism in skeletal muscle by endocrine factors and contractile activity, particularly in the context of insulin resistance and type 2 diabetes

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