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Molecular Biology

Faculty:

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Adam, Rodney: Molecular Parasitology.
Azhar, Mohamad: Role of Transforming Growth Factor Beta Ligands in Cardiovascular Development and Function and Pathogenesis of Aortic Aneurysm
Boitano, Scott: Cell-Cell communication in airway epithelium; Pathogen-Host interaction in the airway; Arsenic effects on the airway epithelium; Wound repair of the airway epithelium.
Bowden, G. Timothy: Molecular mechanisms of physical and chemical carcinogenesis; cellular oncogene activation and differential gene expression during tumor progression.
Brooks, Heddwen: Research focuses on the molecular regulation of the kidney, with a focus on diseases such as diabetes.
Brown, Judith: Diversity and evolution of the genus Begomovirus (Geminiviridae); Biological types’ of the whitefly B. tabaci complex; Virus-vector specificity: functional genomics and proteomics; Geminivirus-vector interactions; Virus-derived RNAi resistance for crop protection; Molecular diagnostics for emergent virus-vector complexes.
Camenisch, Todd: The focus of the laboratory is investigating the integration between extracellular matrix and growth factor receptor signaling during heart morphogenesis. The emphasis is upon heart septae and valve formation. We have established that hyaluronan, a matrix sugar, is able to modulate receptor tyrosine kinase activity during early heart valve morphogenesis. We believe the EGFR family of receptors and cognate ligands play integral functions during heart development. This growth factor signaling activity is most likely context specific in regards to matrix components, proteases, and growth factor presence. Thus experimental approaches are designed to decipher this complex developmental process.

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