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Molecular Genetics

Faculty:

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Adam, Rodney: Molecular Parasitology.
Azhar, Mohamad: Role of Transforming Growth Factor Beta Ligands in Cardiovascular Development and Function and Pathogenesis of Aortic Aneurysm
Bernstein, Harris: Colon cancer
Brilliant, Murray: Genetic and molecular analyses of mouse and human mutations affecting pigmentation and development.
Brooks, Heddwen: Research focuses on the molecular regulation of the kidney, with a focus on diseases such as diabetes.
Burd, Gail: Development of the nervous system: Role of early development genes, sensory afferents, and hormones.
Camenisch, Todd: The focus of the laboratory is investigating the integration between extracellular matrix and growth factor receptor signaling during heart morphogenesis. The emphasis is upon heart septae and valve formation. We have established that hyaluronan, a matrix sugar, is able to modulate receptor tyrosine kinase activity during early heart valve morphogenesis. We believe the EGFR family of receptors and cognate ligands play integral functions during heart development. This growth factor signaling activity is most likely context specific in regards to matrix components, proteases, and growth factor presence. Thus experimental approaches are designed to decipher this complex developmental process.
Chandler, Vicki: Our research investigates mechanisms of gene silencing in plants. We use functional genomics and forward and reverse genetics to study paramutation, transposable elements, transgene silencing, and chromatin control of gene expression.

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