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Structural Biology

Faculty:

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Cordes, Matthew: Protein folding; Structural evolution of proteins; NMR spectroscopy; Evolution of Cro proteins.
Cusanovich, Michael: The Cusanovich laboratory focus on studies of protein structure and function, with an emphasis on biological recognition (protein-protein interactions), the role and mechanisms of protein dynamics in biologically relevant processes, and aspects of bacterial metabolism.
Fane, Bentley: The broad objective of our research program is to elucidate the mechanisms involved in scaffolding-mediated and genome-mediate morphogenesis within the Microviridae system. In addition, we are also beginning to examine the biology of viruses which infect obligate intracellular parasitic bacteria.
Ghosh, Indraneel: The broad objective of our work is to use a repertoire of de novo protein design, directed evolution, and small-molecule approaches to target human disease.
Horton, Nancy: My research involves the structure-function relationships in DNA binding proteins and enzymes.
McEvoy, Megan: Structural Biology and Biochemistry of Metalloproteins
Meuillet, Emmanuelle: Dr. Meuillet's laboratory research interests lie in the general area of modulation of the activity of tyrosine kinases. Over the past eight years, Dr. Meuillet's work has specifically focused on understanding the molecular mechanisms and biological roles of membrane components such as phospholipids and glycosphingolipids, in receptor signaling pathways and how changes in lipid composition can affect downstream transduction signals from the plasma membrane to the nucleus. The recent discovery of lipid rafts and caveolae membrane domains has proven to be important in lipid associated disorders.
Miyashita, Osamu: Theoretical and computational study of protein dynamics

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