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Faculty:
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Aspinwall, Craig
: Development of Novel Methodologies for Investigations of Cellular Signal Transduction - Analytical Chemistry, Bioanalytical Chemistry, Biological Chemistry, Biophysics, Cell Physiology, Sensors, Instrumentation
Departmental affiliations:
Chemistry
,
BIO5 Institute
Program affiliations:
Biological Chemistry
,
Chemistry
Camenisch, Todd
: The focus of the laboratory is investigating the integration between extracellular matrix and growth factor receptor signaling during heart morphogenesis. The emphasis is upon heart septae and valve formation. We have established that hyaluronan, a matrix sugar, is able to modulate receptor tyrosine kinase activity during early heart valve morphogenesis. We believe the EGFR family of receptors and cognate ligands play integral functions during heart development. This growth factor signaling activity is most likely context specific in regards to matrix components, proteases, and growth factor presence. Thus experimental approaches are designed to decipher this complex developmental process.
Departmental affiliations:
Pharmacology & Toxicology
,
Molecular & Cellular Biology
,
BIO5 Institute
Program affiliations:
Pharmacology & Toxicology
,
Molecular and Cellular Biology
,
Graduate Training in Toxicology and Toxicogenomics
Enikov, Eniko
: Biomaterials, Nano-assembly of macromolecules, AFM imaging of biomolecules. Development of micro-systems, MEMS and bioMEMS with application in biology and medicine.
Departmental affiliations:
Aerospace and Mechanical Engineering
,
BIO5 Institute
,
Arizona Cancer Center
Program affiliations:
Ghosh, Indraneel
: The broad objective of our work is to use a repertoire of de novo protein design, directed evolution, and small-molecule approaches to target human disease.
Departmental affiliations:
Chemistry
,
BIO5 Institute
,
Biochemistry & Molecular Biophysics
Program affiliations:
Biological Chemistry
,
Chemistry
Mash, Eugene
: Organic Chemistry
Departmental affiliations:
Chemistry
,
Arizona Cancer Center
Program affiliations:
Chemistry
,
Biological Chemistry
,
Advanced Research Institute for Biomedical Imaging (ARIBI)
Mendelson, Neil
: Biomechanical, biomimmetic, bioconvection, and genetic studies of bacterial model systems.
Departmental affiliations:
Molecular & Cellular Biology
,
Nutritional Sciences
,
Immunobiology
Program affiliations:
Biology, Math, and Physics IGERT Program
,
Molecular and Cellular Biology
,
Biochemistry and Molecular & Cellular Biology
,
Biomedical Engineering
,
Genetics GIDP
,
Immunobiology
Olenyuk, Bogdan
: Recognition of cell surface receptors with synthetic macromolecules; Chemical control of cell adhesion and migration; Design of small molecules for control of protein levels via targeted degradation.
Departmental affiliations:
Chemistry
,
Arizona Cancer Center
Program affiliations:
Chemistry
,
Biological Chemistry
Saavedra, S. (Scott)
: Research interests include physical and chemical processes at solid-liquid interfaces, particularly those involving protein and proteo-lipid films; spectroscopic techniques to probe interfacial structure and processes; structure-property relationships in biomaterials and biological thin films; biomedical instrumentation, particularly optical waveguide transducers; analytical sensing devices based on biological thin films.
Departmental affiliations:
Chemistry
,
BIO5 Institute
Program affiliations:
Biological Chemistry
,
Chemistry
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